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Immunity takes a key role in neural development of both central and peripheral nervous system, regulating several aspects such as neuronal proliferation, synapse formation, and plasticity, together with the removal of apoptotic neurons

Thyroid considerations Cagrilintide carries a theoretical concern regarding thyroid tumors, similar to the boxed warnings on GLP-1 receptor agonists

Examination of GAP43 expression further supports this speculation, as LCN stimulations significantly increased the plasticity marker, GAP43, in the ipsilesional somatosensory cortex, and its expression was positively correlated with improved functional outcomes [75]

Naunyn Schmiedebergs Arch Pharmacol 377:181203 Yano JM et al (2015) Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis