Mussavira S, Dharmalingam M, Omana Sukumaran B
What to Expect in Months 7-11 Essentially no side effects: Appetite suppression continues (desired effect), but GI symptoms gone Weight loss velocity slows: From 0.8kg/week (months 3-6) to 0.3-0.5kg/week Plateau around week 40-48: Weight stabilizes, no longer losing despite continued medication Total weight loss: Average 20-24% from baseline (matching or exceeding surgical outcomes) Focus shifts to maintenance: Accepting current weight, preventing regain Plateau frustration: Not a side effect but an emotional challenge 2 Final Strategies for Months 7-11 20
For comparison, a peptide like ARA-290 has four registered trials, and it's still not approved for anything
In total, 20 samples from Ile/Ile, 12 from Ile/Val and 6 from Val/Val genotype were used in this study
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