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R This pathway is unique for two reasons: The initial activation step occurs in mitochondria via acyl-CoA ligases that require acetyl-CoA (specifically ATP, CoA, and the carboxylic acid substrate form an acyl-CoA intermediate)

During intense physical exertion, the working muscles' need for low-molecular-weight antioxidants, including glutathione, increases

When a bacterium finds itself in an appropriate environment, it starts a colony that will form into a biofilm