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Studies have shown that ACSL4-enriched exosomes can be phagocytosed by microglia, leading to the activation of the nuclear factor kappa-B (NF-B) signaling pathway and polarization of microglia toward a proinflammatory M1 phenotype, thereby amplifying neuroinflammation (He et al., 2024)

Update : People have pointed out that disulfiram implants are apparently fairly popular in Eastern Europe (1, 2, 3)

It has an essential role in energy production, DNA repair, and cellular regeneration

This suggests the weight loss wasnt from making the mice sick or suppressing appetite, but from genuinely changing their metabolism to burn more energy

NPJ Schizophr