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Notably, individuals at the extremes of age, both infants and the elderly, as well as those with pre-existing comorbidities, particularly cardiopulmonary disorders, are at markedly increased risk (490)

The protocol is expensive and the time investment is real

Cagrilintide Phase 2 monotherapy (Lau et al., Lancet 2021) reported about 10.8% weight loss at 26 weeks at 4.5 mg

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Many are naturally produced by the body and can be used in small, highly targeted doses, making them among the most refined interventions in precision medicine