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Interestingly, a concentrationresponse analysis showed there was a notable difference in activity between each regioisomer of 50ac , suggesting that there may be variations in conformational preferences and/or a preference for retaining a 2-aryl substituent on the 2-position of the benzoxazole, consistent with previous SAR studies 38

Elevated Heart Rate: L-carnitine may increase heart rate and blood pressure in some individuals, posing risks for those with existing cardiovascular conditions