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Melatonin, in addition to being an effective inducer of falling asleep, has also been shown to have an antidepressant effect probably linked to its antioxidant and central anti-inflammatory action [169]

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Kunisawa J, Kiyono H

Healthcare providers often need to reduce the doses of these concurrent antidiabetic medications when starting semaglutide therapy, with subsequent adjustments based on glucose monitoring results and clinical response