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Metabolic regulation of stem cells and differentiation: a forkhead box O transcription factor perspective
into the effect of BPC 157 on burn-wound healing and burn-gastric lesions in mice, researchers administered BPC-157 10g or 10 ng/kg via injections or topically, at the burn, as a thin layer of cream (50g of BPC 157 dissolved in 2ml of distilled water)
Pollo A, Carlino E, Benedetti F
Reflecting a compound whose biological effects span multiple molecular targets and pathways rather than operating through a single defined receptor, Established and proposed mechanisms include upregulation of growth hormone receptor expression in tendon and other connective tissue, promotion of angiogenesis through nitric oxide-dependent and VEGF-mediated pathways, modulation of the dopaminergic and serotonergic neurotransmitter systems in the central nervous system, interaction with the NO-synthase and prostaglandin systems to produce cytoprotective effects in gastrointestinal epithelium, activation of the FAK-paxillin pathway to promote cell survival and migration, and anti-inflammatory effects through modulation of inflammatory cytokine production
Individuals with sensitivities should consult a healthcare provider
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