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103 This specific deletion of hepatic Flcn inhibited the activation of SREBP-1c and could prevent or reverse NASH in mice fed choline-deficient L-amino aciddefined and high-fat (CDAA-HF) diet

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In addition, they will also examine the effects of specific enhancement and depletion of GSH on longevity, using lifelong feeding with GSH monoethyl ester and buthionine sulfoximine, respectively