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Massage gently with fingertips for 1-2 minutes to distribute product and stimulate circulation

Ac-DEVD-pNA, Ac-IETD- p NA, Ac-LEHD- p NA were substrate peptides of caspase-3, 8, and 9 respectively, and incubated with Al 2 O 3 NPs-treated cell or lung tissue lysate for 2 h at 37 C

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b , Volcano plot comparing RNA expression (Log 2 of the fold change) of induced and uninduced cells from a and log 10 of adjusted p-value (corrected for multiple testing using the Benjamini and Hochberg method) after dSeq2 differential expression analysis