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Badar T, Shetty A, Bueso-Ramos C, Cortes J, Konopleva M, Borthakur G , Pierce S, Huang X, Chen HC, Kadia T, Daver N, Dinardo C, O'Brien S, Garcia-Manero G, Kantarjian H, Ravandi F

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Histological evidence has shown that the activated T cells cross the BBB, invade the CNS, and congregate around small venules to trigger localized inflammation (Kuhlmann et al., 2017)

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We noticed that the PV2-S71 + PV3-N77 group exhibited a more pronounced tumor inhibition effect and enhanced secretion of immune response cytokines compared to the Durvalumab group