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This species consists of harmless, symbiotic bacterial and different pathogenic variants that can cause intestinal or extra-intestinal diseases, including diarrhea, respiratory tract infections, wound infections, and septicemia, in humans and several animal hosts [65, 66]

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They include infection of hBECs of the BBB, transcytosis, and also infection of transmigration-competent immune cells which may enter the brain as a Trojan horse. A transwell 3D co-culture of HBMECs with astrocytes and monocytes showed how ZIKV-infected monocytes could cross the BBB to enter brain tissue (Bramley et al., 2020)

Recommended Use: Take 1 capsule three times daily, preferably after meals