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Serious Allergic Reactions: Rarely, vitamin B12 shots can cause anaphylactic shock, which can be life-threatening

Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease

By promoting a more robust metabolic function, this promising compound could potentially address age-related changes in body composition and metabolism, such as increased fat tissue as fat cells grow larger

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This means that it is not possible to overdose on vitamin B12, and as far as we know there is no upper limit on the amount of B12 that can be taken safely by an otherwise healthy person