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Its usually administered into the muscle, often in the upper arm or hip

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mutS and mutL alleles contribute to reducing the genetic barrier to recombination (Davidsen and Tnjum, 2006), as it is known that MutS and MutL mismatch binding activity edit (prevent) homologous and homoeologous recombination, limiting the stability of heteroduplex intermediates, with the contribution of the RecBCD nuclease (tambuk and Radman, 1998)