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Synovitis in osteoarthritis: current understanding with therapeutic implications

In vitro , myricetin treatment of SH-SY5Y neuroblastoma cells exposed to 1-methyl-4-phenylpyridine (MPP + ) significantly reduces Fe 2+ and ROS levels, activates the NRF2/GPX4 signaling pathway, suppresses neuronal ferroptosis, and mitigates cellular injury (Gu et al., 2024)

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[DOI] [PubMed] [Google Scholar] 151.Cornish K.M., Williamson G., Sanderson J

Thus, we can conclude that baicalein treatment confers neuroprotection against post-traumatic seizures, oxidative damage, neuroinflammation and neuronal apoptosis in animal models of TBI