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For peptides with spacing of more than 3 residues, the affinity drops with spacer length

PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis

Mastroberardino Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

In animal and preclinical studies, it is associated with tissue-protective effects, modulation of inflammatory signaling, and support of angiogenesis and tendon-to-bone healing pathways

The shrinking or wasting away of cells, organs, or tissues that may occur as part of a disease process, trauma, or aging