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Transcriptomic and epigenomic landscapes of Alzheimers disease evidence mitochondrial-related pathways

SERT: Sertraline

To study the interaction, 200 ng/l dsDNA incubated for 24 h at 37C, 100 rpm, in either absence or presence of 1 mM GSH at intrinsic pH or 1 mM GSH at neutral pH (7.2)

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Interaction with the designed ankyrin repeat protein does not affect p53 DNA binding or the crucial MDM2 negative feedback loop but reactivates a p53-dependent transcriptional program in HeLa (HPV18-positive) and SiHa (HPV16-positive) cells, suggesting a potential therapeutic use