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2017 Sep;16(9):750-760

Potential Side Effects and Considerations Vitamin B12 is generally safe at recommended doses, but side effects like headache, nausea, or stomach upset can occur with high-dose supplementation

Although the initial results with portosystemic shunts may be beneficial, the long-term outcome for patients who require shunts is poor because these patients usually have severe SOS and intervention generally delays, but does not prevent, a fatal outcome

It is not designed for human consumption, medical treatment, veterinary application, or any in vivo use