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In the GHK-Cu complex, the copper ion coordinates with multiple binding sites: the nitrogen from the histidine imidazole side chain, the alpha-amino group of glycine, the deprotonated amide nitrogen of the glycine-histidine peptide bond, and oxygen from the lysine carboxyl group, forming a square-planar pyramid configuration

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doi: 10.1038/s41598-018-36162-0 57 GhoshS

Hepatic ATF6 increases fatty acid oxidation to attenuate hepatic steatosis in mice through peroxisome proliferator-activated receptor alpha