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The study design is summarized in online supplementary Figure 1 (for all online suppl

Since co-treatment of UK-5099 and JMF4073 depleted dTTP pool and suppressed the growth of T315-Bcr-Abl-32D cells, we proposed that reducing GSH biosynthesis induces not only oxidative stress but also replication stress in tumor cells, which demands the synthesis of dTTP and dCTP for survival

This is a condition where excess fat builds up in a persons liver, not due to heavy alcohol use

ng mt vai tr quan trng trong sn xut nng lng v methyl ha, hai qu trnh khng th thiu ct li ca chc nng t bo bnh thng

In vitro studies show that erythrophagocytosis by macrophages induces atypical ferroptosis, potentially causing plaque instability