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Polymorphisms in genes encoding drug-metabolizing enzymes, such as CYP450, can alter the way drugs are processed in the liver, making genetic screening a potential tool for identifying individuals at higher risk for DILI [92]

yes, I also have a protocol Im following atm

Azodo, MD, University of Chicago, Chicago, IL and Yvonne Romero, MD, FACG, Mayo Clinic, Rochester, MN Published January 2006

Because the testing lab carries no commercial stake in the manufacturing outcome, release decisions track the analytical data rather than supplier-side judgement, with acceptance criteria committed in writing before each synthesis run begins

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