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The first uptake is of glutamate and GABA into astrocytes, where a large fraction is converted to glutamine in an energy-requiring process, and the second uptake is that of glutamine into neurons

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For studies investigating systemic or multi-tissue repair responses such as those modelling complex injuries or post-surgical recovery in animal systems the combination offers a broader pharmacological reach than either peptide in isolation

2011, edn

Autoimmune-mediated DILI may be caused by specific drugs, and the immune responses mimic those typically observed in de novo or idiopathic autoimmune hepatitis