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These data support a role for GSH as an upstream regulator of pyroptosis by coupling metabolic redox status to inflammasome activation

Accessed 12/3/2021, Azadi-Yazdi M, Karimi-Zarchi M, Salehi-Abargouei A, Fallahzadeh H, Nadjarzadeh A

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This results in systemic signaling effects that extend beyond adipose tissue, making these compounds more suitable for studying integrated endocrine regulation rather than isolated metabolic pathways