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3) Growth-Hormone Receptor (GHR) Up-regulation & JAK2 Signaling (Tendon Fibroblasts) In rat tendon fibroblasts, BPC-157 up-regulated growth hormone receptor and enhanced downstream JAK2 activation upon GH exposure, correlating with proliferative markers

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418 CD38 expression inversely correlates with prostate cancer progression due to its ability to lower intracellular NAD + , resulting in cell-cycle arrest, reduced glycolytic and mitochondrial metabolism, and impaired fatty acid and lipid synthesis