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These findings were further highlighted by the identification of metabolic correlates to HbC % (Figure 2D), the top of which presented in the form of violin plots in Figure 2E

It is essential to keep cellular energy metabolism balance to ensure the stability of mitochondrial membrane potential and preserve the proper functioning of neural cells

GSH depletion-dependent cell death was prevented by selective ferroptosis inhibitors (8 M Fer-1 and 600 nM Lip-1), iron chelator DFO (80 M), as well as autophagic inhibitors Baf-A1 (75 nM) and 3-MA (10 mM)

It helped restore normal sleep architecture, a critical distinction from pharmaceutical sleep aids that often suppress certain sleep stages while artificially extending others

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