Canonical autophagy machinery plays a crucial role in ferroptosis 48
Pyroptosis forms pores in the cell membrane via Gasdermin D, releasing pro-inflammatory factors and triggering local inflammation, which impairs endothelial function
Antioxidant and iron-chelating agents in cerebral vasospasm
Given that flagella were the only LCA-specific upregulated cellular component at the protein level during early biofilm formation, the flagella-independent mechanism of LCA-induced adhesion may involve a physical interaction between LCA and pre-existing features of the EcN cell surface
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