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In the p53 TAD apo state, most residues showed low values ( 0.2 was observed for residues corresponding to TAD2 and the C-terminus (Figure

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It was discovered that UPS controls the function of RTECs via the transcription factors sterol regulatory element-binding protein 1 (SreBP-1), GATA4/GSA1 route, STAT1/TGF-1 pathway, and PINK1/Parkin pathway