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In this context, for instance, the pharmacokinetic profile needs to be defined in detail, including the type of metabolic enzymes involved in its degradation, interactions resulting from the binding of the drug to plasma proteins, etc

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10.1017/s0029665115001433 53.Kornerup LS, Hvas CL, Abild CB (2019) Early changes in vitamin B12 uptake and biomarker status following Roux-en-Y gastric bypass and sleeve gastrectomy