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Gastroenterology 46 (4), 436445

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High-throughput phenotyping Importantly, the integration of CRISPR screening with high-content phenotyping modalities, including live-cell imaging, multiplex transcriptomics, and single-cell RNA sequencing, enables real-time visualization of how cells dynamically reorganize proteostasis resources

Principal effect modifiers are speculated to be differences in patient populations (peri-operative CABG vs PCI vs medically managed acute myocardial infarction) as well as resultant ischemic burden (Furat et al