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In fact, the reactive species interactome has been the subject of a very interesting review stating that the adaptive, selective and evolutionary cellular mechanisms that are required to overcome oxidative stress are largely dependent on cysteine redox switches, leading to enzyme modification and improved antioxidant capacity

Plasminogen activator inhibitor-type I is a major biosynthetic product of retinal microvascular endothelial cells and pericytes in culture

pneumoniae infection induces memory in respiratory epithelial cells, which enhances bacterial adhesion and facilitates infection upon reinfection (28)

This Review highlights new developments regarding the potential role of reactive metabolites, mitochondrial toxicity, host immune-response pathways and biliary transporters in the etiopathogenesis of DILI