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Moreover, a novel mouse model engineered to have enhanced cholesterol synthesis by SREBP-2 overexpression superimposed to APP/PS1 mutations triggered A accumulation and tau pathology ( in vivo replenishment of mGSH with cell- permeable GSH monoethyl ester (GSHEE) attenuated neuropathological features of AD in SREBP-2/APP/PS1 mice

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De Falco M, Lucariello A, Iaquinto S, Esposito V, Guerra G, De Luca A (2015) Molecular mechanisms of Helicobacter pylori pathogenesis