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The quaternary structure practically exists thanks to presence of cysteine related disulfide bridges linking separate polypeptide chains

It has been shown that the use of different inhibitors to inhibit apoptosis, necrosis and autophagy is more effective than the use of any of these inhibitors in isolation, as in the case of cerebral hemorrhage, where caspase inhibitors have been shown to be unsuccessful in terms of inhibiting hemoglobin-induced neuronal death (142)

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