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These findings are consistent with a January 2017 JAMA study that looked at approximately 290,000 adults and found low-intensity smoking over the lifetime was associated with a significantly higher risk of all-cause mortality, including deaths from lung cancer and cardiovascular disease [compared to never smokers]. But this was the first study to combine results relating to both stroke and coronary heart disease, providing incentive for smokers to quit entirely instead of just cutting down

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However, the further associations between alcohol/tobacco use and symptoms/cognition in these disorders remain unexplored

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Tobacco use is the leading preventable cause of disease and death in Canada, killing 46,000 Canadians each year, including about 30% of all cancer deaths