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Diabetes, Obesity and Metabolism 13:99-117

Statements Author contributions WL: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing

Its findings the safe dose range, how the compound behaves in humans, early signs of biological activity feed directly into Phase 2, where the drug is studied in patients for the first time, and therefore for the first time therapeutic efficacy is tested and the most optimal dose is investigated

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Degraded peptide delivers less active compound