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HbA1c fell about 2.0 to 2.6 percentage points and approached its floor by 10 mg, while weight continued responding to higher doses. Participants starting above 8% HbA1c often fell by more than 3 points

Ethics declarations Ethics approval and consent to participate We obtained institutional review board (IRB) approval from the Ethical Committee at the University Hospital Frankfurt (20549) and written informed consent was waived for this retrospective study

Metabolism of cisplatin to a nephrotoxin in proximal tubule cells