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Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity

The trainer can be perfectly well intentioned and still cannot fix any of the four risks listed above, because none of them are within a trainers scope to control

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Active substance use: typically requires treatment beforehand Pregnancy planning: advised to avoid pregnancy for 1218 months post-surgery According to ASMBS, a thorough pre-operative assessment, including psychological evaluation, helps ensure readiness

16-week on / 4-week off: Extends into the range of the Phase IIb trial duration while building in a recovery window