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10.1080/07853890.2024.2337871 50 LiangY.ZhangC.WeiH.DuH.ZhangG.YangY.et al (2022)

B Vitamins play a critical role in energy production

A significant study observed notably reduced vitamin C levels in patients with atopic dermatitis, recording plasma vitamin C concentrations between 0.11-0.55 mg/dL (6-31 umol/L), well below the optimal concentration of over 1.06 mg/dL (60 umol/L)

Protection against aminoglycoside-induced ototoxicity by regulated AAV vector-mediated GDNF gene transfer into the cochlea

Published clinical trial data describe weekly dose-escalation protocols ranging from sub-milligram to low-milligram levels in controlled study populations