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UA increases iNOS expression in the -cells, decreases GSIS, and causes apoptosis [39]

Ascorbic acid depletion was monitored at an absorbance of 290 nm (molar extinction coefficient = 2.8 mM cm 1 ) for 1 min

M., Waldvogel, H

In this context, the CS regulation at both the enzyme and the gene level plays a pivotal role in the metabolic flux modulation of tumors, and scientists can target them for therapeutic purposes