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First-in-human trail of M9140, an anti-CEACAM5 antibody-drug conjugate with Exatecan payload, in patients with metastatic colorectal cancer

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To interrogate the mechanisms underlying NRF2-directed regulation of this core gene set, we compared mean promoter (1 kb restricted) ChIP-seq signal in A549 for NRF2, p300, as well as the histone marks H3K4me3 and H3K27ac, which are enriched at promoters and enhancers, respectively

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Try to stay active and involved in daily life activities, but pay attention to your physical and mental health needs, as well