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adding a second axis means a second clean draw, not a cocktail

Nat Rev Endocrinol 2013;9:366-376

Interestingly, although mammalian GR somewhat resembles the TrxR domain of SmTGR, the GR domain of SmTGR has the fold of Trx and is appended to the N-terminus of the TrxR core of SmTGR, containing the C28-C31 pair (Angelucci et al., 2010