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No comparative data exist to determine whether this offers any advantage over single-route dosing

What role should nutrition, sleep, stress, and gut-supportive habits play

Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice

Medical Center)

Identify gaps in the literature and ongoing research directions Key gaps include a lack of large, controlled clinical trials, unclear optimal dosing and delivery for reproductive targets, limited long-term safety data for systemic use, and few mechanistic human studies linking molecular changes to fertility outcomes