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However, we can glean some insights from studies of cagrilintide with other GLP-1 agonists and the individual safety profiles of these medications: Cagrilintide has shown a favorable safety profile in clinical trials, with most adverse events being mild to moderate in severity
, 53 using claudin-2-null mice, suggest that the loss of claudin-2 in colonic epithelium enhances susceptibility to the DSS-colitis complemented these findings