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Cotinine, a metabolite of nicotine, can be detectable for even longer, typically 7-10 days after the last use in occasional smokers and up to several weeks in regular smokers

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In our future studies, we're going to try to temporarily lower ApoE. As a treatment to improve bone healing, the patient could take a pill or an injection to lower ApoE for a short time rather than permanently, and there would be dietary restrictions during treatment