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Therefore, chromatographic separation and NMR may be necessary

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HPLC tested for purity and analytical consistency

This decision reverses a previous ruling that placed approximately 19 peptides on the more restrictive Category 2 list, effectively banning their use in compounded medications due to potential significant safety risks. The reversal came after significant debate and legal challenges from medical providers and pharmacy groups, who argued that the FDA had not presented sufficient evidence to justify the ban