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35,36 A final note: An elevated temperature in dogs can be a result of fever (associated with infection or inflammation) or can be due to hyperthermia (an elevated temperature due to activity, anxiety, excitement, or overexposure to a hot environment)

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The most mechanistically coherent pairing is MOTS-c with resistance training and aerobic exercise

Innate inflammatory signals, including DAMPs, alarmins (S100A8 and S100A9), and complement, further contribute to OA pathogenesis

This monitoring should be individualized based on the patients baseline cancer risk factors, personal medical history, and family history of malignancy