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In certain instances, the penetration enhancing agent is a hyaluronidase
Some studies have reported that, in patients with EMS, both normal endometrial stromal cells (NESCs) and ectopic endometrial stromal cells (EESCs) exhibit significantly increased Fibulin-1 expression, which confers ferroptosis resistance on EESCs by inhibiting ferroptosis (27)
Collectively, these results suggested that EV-derived VDAC1 protein is a potential therapeutic target for averting PTX resistance of GC and a specific inhibitor of VDAC1, such as DIDS, might serve as a component of combination therapy to overcome PTX resistance
The other ingredients are fat suppository base, methyl salicylate and glyceryl tristearate
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