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It may also offer neuroprotective benefits and improve mood and cognition [29, 36, 37]

Additionally, the pleiotropic actions of GLP-1 expand the therapeutic potential of GLP-1 agonists/analogues through combination with other drug classes, suggesting new scenarios in terms of enhancing cardio-renal protection and expanding clinical indications

This amplification of endogenous signaling rather than exogenous receptor activation is a mechanistically distinct approach to cognitive enhancement

Koch Professor of Biology at MIT and a member of the Koch Institute for Integrative Cancer Research

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