Urolithin A is a mitophagy activator, which is verified to regulate mitophagy through the PINK1/Parkin pathway
J Biol Chem 286 , 1114111154, doi: 10.1074/jbc.M110.196543 (2011)
This review synthesizes current evidence on the contributions of these AAs to intestinal barrier integrity, immune regulation, oxidative stress mitigation, and gut microbiota modulation in CD
The radioprotective effects of other phenolic glycosides including quinic and chlorogenic acid have also been studied on human lymphocytes in vitro
Improvements were observed in metabolic control, lipid profile, vascular function, oxidative stress, and inflammatory markers all without adverse effects on renal, hematologic, or micronutrient balance