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Exogenous glutathione is available in various forms, including oral supplements and foods such as fruits, vegetables, and meats

These biological and environmental discrepancies limit external validity and severely constrain the generalizability of preclinical findings to real-world clinical settings

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3.2 Miscellaneous sources There are many exogenous sources of ROS generation, for examples, transition metal ions likely iron (Fe), zinc (Zn) and copper (Cu) have the abilities to induce oxidative stress in living cells via performing Fenton and Haber-Weiss reactions

and some of the overlapping expression profiles of 5-HT 2C and GHSR1a (Abramowski et al., 1995