Individual response times vary based on condition severity and overall health status
However, there is no robust evidence that B12 injections provide benefits to individuals with normal B12 levels
The genetic correlates relate primarily to variants in the genes coding for transporters controlling plasma UA, yet such presumed functional variants will also influence, through the same proteins, the transport of UA into the brain and subsequently into neurons and glia, as described below
During wound healing, it can be removed from existing extracellular proteins by proteolysis and used as a chemical attractant for inflammatory and endothelial cells It can increase the production of messenger RNA in collagen, elastin, proteoglycans and glycosaminoglycans in fibroblasts
(PubMed) Valuck RJ, Ruscin JM